Desvenlafaxine generic

Desvenlafaxine is an effective antidepressant that helps get rid of anxiety, as well as symptoms of severe and protracted depression. Desvenlafaxine antidepressant is available for sale without prescription in many online pharmacies.

Desvenlafaxine belongs to antidepressants, which are the serotonin and norepinephrine reuptake inhibitors (SNRI) – the two most important mental state regulators. Serotonin regulates such functions, as mood, appetite, and “sleep-wake” cycle. The main goal of noradrenaline is to provide the body with energy and vitality.

Desvenlafaxine is able to affect the serotonin and noradrenaline receptors, maintaining a constant concentration of these neurotransmitters in the blood plasma. Serotonin and norepinephrine receptors activation increases mood, improves appetite, reduces anxiety and phobias.

The antidepressant activity of Desvenlafaxine almost does not apply to other groups of receptors besides serotonin and noradrenaline. Thus, the use Desvenlafaxine does not cause side effects, typical of other antidepressants: constipation, palpitations, visual impairment and others.

Desvenlafaxine is well absorbed by the body after the intake. The maximum concentration of antidepressant reaches its peak in about 7 hours after the administration. Sustainable Desvenlafaxine concentration in the blood is reached in about the 5th day of treatment. The first signs of depression symptoms decrease manifest by this time.

If you buy Desvenlafaxine without prescription and use it only once or twice, it does not save you from anxiety and depression. Desvenlafaxine exerts its antidepressant effect only after a treatment course.

Desvenlafaxine is an active metabolite of another SNRI – Venlafaxine. For a long time, Desvenlafaxine and Venlafaxine were thought to have identical properties and the ability to exert the antidepressant effect. However, recent clinical studies have shown significant differences between these antidepressants.

Both Desvenlafaxine and Venlafaxine are equally effective to maintain serotonin concentration. However, Desvenlafaxine inhibits the norepinephrine reuptake significantly stronger than Venlafaxine. This explains the difference in dosages of these antidepressants. The daily Venlafaxine dose is 75-225 mg per day, while Desvenlafaxine – 50-400 mg.

Due to the varying efficacy of action, Venlafaxine and Desvenlafaxine have different indications for use. Venlafaxine is indicated for the treatment of mild to moderate depressive disorders. Desvenlafaxine should only be used in severe depression, when Venlafaxine turns ineffective.

By purchasing Desvenlafaxine without prescription, you will get the following benefits:

  • antidepressant, the efficacy of which is superior to that of other drugs groups, such as tricyclic antidepressants (TCAs) and selective inhibitors of serotonin reuptake (SSRI)
  • effective sequential treatment of the main prolonged and severe depression symptoms;
  • safe drug, which may be combined with other antidepressants or with other drugs.

In all countries of the world where this antidepressant is available for sale, you may buy Desvenlafaxine without prescription in the form of extended release (ER) tablet. Medications for the depression treatment may contain Desvenlafaxine Succinate, Benzoate and Fumarate. All three chemical formulas of Desvenlafaxine are equivalent to each other in the mass fraction and the active ingredient rate of absorption into the body.

Desvenlafaxine is indicated for the treatment of major depressive disorder only in patients older than 18 years. The recommended starting antidepressant dose is 50 mg per day. The daily dosage of this antidepressant may be gradually increased up to 400 mg, if the doctor considers appropriate to increase Desvenlafaxine dosage.

Treatment of severe and prolonged depression symptoms with Desvenlafaxine may last about 6 months. However, clinical trials have demonstrated the effectiveness and good tolerability of this antidepressant for nearly one year.

Desvenlafaxine tablets are recommended to be taken every day at the same time, regardless of meals. After the main depression and anxiety symptoms disappear, Desvenlafaxine should be discontinued by gradual dosage reduction. Sudden discontinuation of this antidepressant may cause withdrawal symptoms, that is, depending on the drug.

Desvenlafaxine was approved by the FDA on December 22, 2005. The drug was developed in the hope to improve the antidepressant activity of its predecessor – Venlafaxine. Starting from January 23, 2007, you may buy Desvenlafaxine without prescription under the brand name Pristiq.

Desvenlafaxine was approved in Canada on February 4, 2009. Desvenlafaxine is sold in Canada under the name Pristiq, just like in the USA. If you plan on buying Desvenlafaxine without prescription in Australia, local online pharmacies, it may be sold under Desfax, and Ecenze brand names.