Diazepam is an effective anxiolytic, available on online pharmacies without prescription. Diazepam is used to treat symptoms of depression and anxiety, including insomnia and anxiety disorders in alcohol abuse. Also Diazepam can be used as an anticonvulsant and muscle relaxant.
Diazepam is related to a group of benzodiazepine derivatives. Diazepam with a wide spectrum of therapeutic activity provides the following effects:
- muscle relaxant.
A wide spectrum of Diazepam action is in a specific effect on benzodiazepine receptors of the nervous system and brain. Diazepam increases the impact of gamma-aminobutyric acid (GABA) – the main inhibitory neurotransmitter, on the brain. GABA, under the influence of Diazepam, reduces the activity of neurotransmitters excitation.
Diazepam is absorbed well, and its peak concentration in the blood is reached approximately in 1-3 hours after oral administration. Antidepressant and other effects of Diazepam last for approximately 12 hours. Diazepam is related to drugs with a long half-life. Diazepam blood concentration is maintained for several days after treatment cessation.
To get rid of anxiety symptoms, 2 to 10 mg of Diazepam is enough to take 2-4 times a day. The same dose of 10 mg Diazepam is taken at bedtime to eliminate insomnia. Relief of muscle tension and tetanus elimination are expected after 2-10 mg of Diazepam three times a day.
Patients who experience stress and anxiety in alcohol abuse, may take on the first day of treatment 30-40 mg of Diazepam per day, split into 3-4 intakes. Then, the daily dose can be reduced to 15-20 mg.
Children from 3 years of age and older patients can take 1-2 mg of Diazepam twice a day. Depending on the achieved effect and tolerability, Diazepam dose for young or elderly patients can be reduced or increased.
Diazepam is also recommended to patients feeling anxiety of the upcoming surgery. This group of patients is indicated a dose of 10-20 mg Diazepam, in the evening at bedtime before surgery.
In rare cases, Diazepam is prescribed to pregnant women to reduce anxiety, cramps, and other signs of a difficult pregnancy.
If you plan to buy Diazepam without prescription, you can find Diazepam pills of 2 mg and 5 mg on online pharmacies. In some countries, for example, in the Netherlands and the USA, rectal gel Diastat, containing Diazepam is available as well. Diastat gel is applied to get rid of severe seizures in patients who are on medications to treat epilepsy.
A single dose of Diastat gel is contained in applicators, which may contain 2.5mg, 5mg or 10mg of Diazepam. Diastat should be administered during episodes of increased seizure activity using a special syringe. Diastat should not be used every day, the gel is indicated for application 5 times a month, maximum.
In addition to pills and rectal gel, Diazepam injections are commercially available. For example, in Ireland, Diazemuls is available as emulsion for injection. Each 2 ml emulsion contains 10 mg of Diazepam.
Diazemuls can be administered intravenously, intramuscularly, or by infusion. An optimal rate of administration is 4 ml of solution per hour. To remove depression symptoms and to eliminate seizures, a dose of injectable Diazepam makes 10 mg per day.
Having chosen an optimal dosage form and ordered Diazepam without prescription, you can use this anxiolytic for:
- treatment of neurological disorders
- anesthesiology and surgery.
By its sedative, anticonvulsant and muscle relaxant effects, Diazepam is similar to another benzodiazepine – Lorazepam. But Diazepam starts working faster and its effect is maintained longer comparing to Lorazepam. Furthermore, Diazepam is less toxic and its use rare causes drug addiction and withdrawal symptom.
Despite Lorazepam is more effective as an anticonvulsant, it is significantly inferior Diazepam as a sedative. Lorazepam is slowly absorbed into the body and has no dosage form for rectal administration.
Diazepam is related to the second generation psychopharmaceutical drugs. It was developed in 1963 by Professor Leo Sternbach from pharmaceutical company Hoffman-La Roche. By providing an antidepressant effect, Diazepam significantly exceeded Chlordiazepoxide, the only benzodiazepine tranquilizers at that time.
Since its development, Diazepam immediately became the best-selling anti-depressant ever from the group of benzodiazepines. For example, about 2.3 milliards Diazepam contained pills were sold in total in the USA in 1978.
The huge popularity of Diazepam in the world can be explained by its safe application comparing to other benzodiazepines. Besides Diazepam rarely causes addiction and dangerous side effects.
Today Diazepam is believed to be the most prescribed benzodiazepine in psychiatric and neurological practice. If you plan to buy Diazepam online without prescription, you can order its delivery in the countries of North and Latin America, Southeast Asia, Australia and Europe.