Hydrocodone is a reliable and effective pain reliever eliminating symptoms of moderate to severe pain. Those suffering from pain persistent at other analgesics are recommended to buy Hydrocodone without prescription.
Hydrocodone is a semi-synthetic opioid, derivative of Codeine. Hydrocodone exceeds Codeine by its analgesic action. Another example of the analgesic from the same class of Codeine derivatives is Thecodine.
Hydrocodone helps to eliminate pain symptoms affecting opioid receptors in the brain. Hydrocodone completely blocks some opioid receptors, preventing from transmitting pain signals to the brain. Hydrocodone is a full agonist of opioid receptors, i.e. it provides a maximum analgesic effect.
Thus, buying Hydrocodone without prescription, you can:
- reduce your pain perception;
- increase pain tolerance;
- reduce adequate emotional reactions to pain.
Hydrocodone peak concentration is achieved approximately in 5 hours after taking the analgesic. Sustained release dosage forms increase concentration in plasma in 6-30 hours after oral administration.
Hydrocodone is a potent opioid analgesic, so its use should be prescribed only by the attending physician. In the USA, Hydrocodone without prescription is available under two brand names:
- Hysingla ER pills, containing 20, 30, 40, 60, 80, 100 120 mg of Hydrocodone Bitartrate;
- Zohydro ER capsules, containing 10, 15, 20, 30, 40 и 50 mg of Hydrocodone Bitartrate.
Hysingla ER pills and Zohydro ER capsules have a prolonged-release form of the active ingredient. If the patient is about to try Hydrocodone opioid analgesic first time, it is better to start Zohydro ER capsules with 10 mg per day, Hysingla ER pills – with 20 mg per day.
If the patient combines the opioid with other analgesics, a dose of Hydrocodone should not exceed 8 mg a day. Higher doses of Hydrocodone in combination therapy may lead to undesirable reactions, such as respiratory depression.
Hydrocodone-based drugs can be used till complete elimination of the pain symptoms. If the analgesic is no longer needed, its application should be stopped within 10 days, gradually reducing the daily dose of Hydrocodone. If you suddenly stop taking the painkiller, you can feel withdrawal symptoms: nausea, cough, high blood pressure, etc…
Hydrocodone may be in the compound of combined drugs for pain treatment. Combined Hydrocodone-contained medications and non-narcotic analgesics, such as Acetaminophen is, or Ibuprofen, are widespread in the USA.
Acetaminophen provides less evident analgesic effect comparing to Hydrocodone. But in combined medications such as Anexsia, Norco or Zyfrel, Acetaminophen enhances the analgesic effect of the opioid analgesic. Hydrocodone suppresses the opioid receptor action, while Acetaminophen blocks production of enzymes causing pain.
Clinical trials have shown that combination of Hydrocodone and Acetaminophen is more effective for pain relief than the use of each of these components alone. The only negative impact of Hydrocodone and Acetaminophen – they may cause liver toxicity.
You can buy Hydrocodone without prescription as combination of Reprexain and Vicoprofen. In addition to opioid analgesic, they also contain Ibuprofen, which is a non-steroidal anti-inflammatory drug (NSAID).
Hydrocodone and Ibuprofen combination is more effective and its analgesic effect lasts longer, compared to each of the analgesic alone. Due to Ibuprofen, such drugs as Reprexain and Vicoprofen provide not only analgesic, but also antipyretic and anti-inflammatory effects.
If necessary, you can buy Hydrocodone without prescription and use it to treat cough. In the USA, combined drug Tussigon is available, which in addition to the opioid analgesic contains anticholinergic agent Homatropine.
Usually Homatropine is used to expand the pupil of the eye for diagnostic purposes, but its combination with Hydrocodone eliminates cough symptoms.
To get rid of cough symptoms in children over 6 years old, 1-5 pills of 1.5 or 5 mg of Tussigon per day are enough. More than 5 tablets of Tussigon per day should not be taken.
Hydrocodone was first synthesized in 1920 by Dr. Nathan Eddy, working at German pharmaceutical company Knoll Pharmaceuticals. The opioid analgesic was launched in 1924 under name Dicodid.
Almost 20 years passed after the release, when Hydrocodone appeared in the USA. However, Comprehensive Drug Abuse Prevention and Control Act was signed in 1970, according to which Hydrocodone-based analgesics have to be under strict control.
However, now Hydrocodone-based opioid analgesics are among the most prescribed in the USA medications to relieve pain symptoms. Over 100 million prescriptions on the drugs containing the opioid analgesic was registered in 2010. In the USA you can buy Hydrocodone without prescription on many online pharmacies.