Hydromorphone is a semi-synthetic opioid analgesic used to treat moderate to severe pain. Hydromorphone is approved to be a controlled drug in all US states, so this opioid analgesic is unavailable at the retail pharmacy without prescription.
Many acute and chronic diseases, injuries and medical interventions associated with pain require analgesics to be used. When non-opioid analgesic drugs (paracetamol, ketoprofen, tramadol) do not help to stop chronic pain, Hydromorphone is used.
Hydromorphone is an opioid analgesic and one of the main drugs for treatment of pain syndromes of medium and high intensity in different areas of medicine.
By its analgesic effect, Hydromorphone far exceeds all known non-opioid analgesics. Opioid Hydromorphone provides a central mechanism of action through interaction with the CNS opioid receptors.
In particular, Hydromorphone has a high affinity for the mu opioid receptors. The action of the opioid analgesic is very similar to that of morphine.
However, according to clinical trials, Hydromorphone is 8 times more active than morphine when taken orally, and an injectable form of Hydromorphone exceeds 6 times morphine action.
If you or your family have used the opioid analgesic before, and now need to buy Hydromorphone without prescription, buy it online.
Ordering Hydromorphone on an online pharmacy, you can quickly start treatment of acute and chronic pain refractory to non-opioid analgesics.
Hydromorphone is quickly absorbed both in ingestion and in subcutaneous administration. The duration of the analgesic effect of Hydromorphone depends on the dosage form.
Hydromorphone is supplied to markets of Canada, the United States, and Australia as:
- 5mg / 5ml; 1mg / ml oral solution
- 2mg; 4mg; 8mg oral tablets
- 8mg; 12mg; 16mg; 32mg extended release tablets
- 1mg / ml; 2mg / ml; 4mg / ml, 10mg / ml of subcutaneous injections
Hydromorphone provides its analgesic effect quickly, within 10-15 minutes after subcutaneous administration and in 20-30 minutes after oral administration.
Thus the depth of analgesia is Hydromorphone-dose dependent and can be adjusted according to the pain intensity. The therapeutic effect of the sustained release tablets lasts on average 12 hours, of the fast release tablets – 4-5 hours.
Hydromorphone sustained release tablets (Palladone, Exalgo) are not recommended to split, since quick penetration of the entire dose of the drug into the systemic circulation may cause overdose.
If you never used Hydromorphone before and decided to buy the opioid analgesic without prescription, you should carefully read the instructions to learn the indications for its use.
Hydromorphone is used for relief of chronic (persistent), moderate to severe chronic pain in:
- myocardial infarction
- oncological diseases
- severe strokes
- in the preoperative and postoperative period
In particular, Hydromorphone can be administered in extreme pain in patients with osteoarthritis, when inflammatory changes are insignificant, and surgery is not indicated.
Moreover, Hydromorphone can be used as an adjuvant in premedication, epidural and spinal anesthesia. Like other opioids, Hydromorphone can be used for recreational purposes. This opioid causes euphoria, reduces anxiety, and causes sedation and respiratory depression.
These effects make Hydromorphone particularly dangerous in terms of abuse. At the same time, many patients can use opioid analgesic Hydromorphone for a long time without addiction provided for strict compliance.
If you bought Hydromorphone without prescription, you should strictly comply with the dosing regimen as the opioid analgesic may cause physical and psychological addiction.
A characteristic of Hydromorphone is tolerance, it means an analgesic effect decreased with increasing administration duration. Therefore, in long-term therapy, a dose should be gradually increased to maintain an effective analgesic effect.
When using Hydromorphone, its side effects are rarely avoided, usually observed at the beginning of pain therapy. Most often, patients experience dizziness, drowsiness, and nausea.
The most dangerous side effects of Hydromorphone is caused by overdose – deep depression, respiratory and circulatory depression. In this regard, all patients are strictly advised not to exceed the therapeutic doses and not abuse Hydromorphone. Hydromorphone application in the prescribed dosage ensures a long analgesic effect and reduces the risk of side effects.
Hydromorphone is one of the most effective opioid analgesics. This analgesic is supplied to Australia, the United States and Canada under various trade names. The most famous brands are Hydromorphone Dilaudid, Jurnista, Palladone, Exalgo.