* Patients, taking Testosterone pills, may suffer from swelling. Therefore men, who have water retention in the body before they start to take Testosterone pills, might need individual adjustment of Testosterone daily dose for androgenic therapy.
* If Testosterone pills are prescribed for pediatric patients or adolescents in pubertal period, their use must be carried out under permanent control of the physician.
* Long-term use of Testosterone pills involves regular control of the size and consistency of the prostate gland in adult men.
* Barbiturates (Butabarbital, Pentobarbital, Secobarbital) can change the concentration of Testosterone in the blood. Hence before starting the treatment with Testosterone pills along with barbiturates, one should consult a health professional.
* Testosterone pills can can negative effect on kidneys. Therefore the risk of renal failure increases, if Testosterone pills are taken with other drugs that affect renal function (for example, Cyclosporine immunosuppressant).
* During the period patient is taking Testosterone pills, peripheral tissues may develop tolerance to glucose. So if Testosterone pills are prescribed for men with diabetes, they might need to reduce the daily dose of antidiabetic drugs and (or) insulin.